Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447010 | 0.84 | APLNR (0.47) | KDM4ETP53TDP1PKM | |
| SCHEMBL8449970 | 0.80 | CYP1A2 (0.49) | TP53LMNAPKM | |
| SCHEMBL8448659 | 0.79 | CNR1 (0.52) | GRIK2GRIK1LMNAAKR1C3PKM | |
| SCHEMBL8445101 | 0.79 | NPBWR1 (0.46) | KDM4ELMNAPKM | |
| SCHEMBL8446733 | 0.78 | PLA2G2A (0.48) | TP53 | |
| SCHEMBL8627206 | 0.76 | BUB1 (0.44) | KDM4E | |
| SCHEMBL8448874 | 0.76 | MAPT (0.49) | LMNAAKR1C3AKR1C2PKM | |
| SCHEMBL8448901 | 0.75 | ACHE (0.43) | ELANEPKM | |
| SCHEMBL8441605 | 0.75 | PTGS2 (0.50) | — | |
| SCHEMBL6966885 | 0.75 | KDM4E (0.50) | KDM4ETP53LMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |