Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187014 | 0.85 | RAB9A (0.33) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL8630238 | 0.77 | RAB9A (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL4448588 | 0.77 | NPC1 (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL8629170 | 0.77 | CASP3 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL5267951 | 0.74 | ALOX15 (0.47) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL15392970 | 0.73 | NOTUM (0.36) | SMN1; SMN2RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL3613332 | 0.73 | ALDH1A1 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL28185933 | 0.73 | RAB9A (0.75) | SMN1; SMN2RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL352664 | 0.71 | NPC1 (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL11324245 | 0.70 | L3MBTL1 (0.55) | RAB9ANPC1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| EP-0003277-A1 | Heterocycle substituted (3-loweralkylamino-2-RO-propoxy)pyridines, process for preparing the same,and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1979-08-08 | — | — | EP | disclosed |