Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618 | 0.96 | ALDH1A1 (0.56) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| SCHEMBL7044927 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL340601 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| Hydrochloric Acid SCHEMBL2245621 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| Potassium Ion SCHEMBL9548465 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| SCHEMBL2952540 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| P-Xylene SCHEMBL1904190 | 0.88 | BCHE (0.54) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| Formamide SCHEMBL27702419 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| SCHEMBL11591763 | 0.82 | LMNA (0.52) | ALDH1A1TSHRNT5ELMNAKDM4E | |
| SCHEMBL10863214 | 0.80 | LMNA (0.50) | ALDH1A1TSHRNT5ELMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753606-A | DETERGENT MIXTURE WITH NONIONIC SURFACTANTS AND ANIONIC SURFACTANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-05-19 | — | — | US | disclosed |