Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8632105 | 0.90 | ALDH1A1 (0.52) | ALDH1A1TSHRNT5EMCOLN3LMNA | |
| SCHEMBL29618 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TSHRNT5EMCOLN3LMNA | |
| Potassium Ion SCHEMBL338736 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MCOLN3LMNAKDM4EGAA | |
| Sulfuric Acid SCHEMBL8078542 | 0.88 | LMNA (0.46) | ALDH1A1MCOLN3LMNAKDM4EGAA | |
| Hydrochloric Acid SCHEMBL2245621 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRNT5EMCOLN3LMNA | |
| Ammonia Solution, Strong SCHEMBL340601 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRNT5EMCOLN3LMNA | |
| SCHEMBL7044927 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRNT5EMCOLN3LMNA | |
| Hydrogen Peroxide SCHEMBL11036237 | 0.86 | LMNA (0.47) | ALDH1A1MCOLN3LMNAKDM4EGAA | |
| SCHEMBL67964 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MCOLN3LMNAKDM4EGAA | |
| Zinc Ion SCHEMBL1589972 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MCOLN3LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550634-A1 | POLYHYDROXY FATTY ACID AMIDES IN BRIGHTENER-CONTAINING LIQUID DETERGENT COMPOSITIONS. | PROCTER & GAMBLE (US) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006172-A1 | POLYHYDROXY FATTY ACID AMIDES IN BRIGHTENER-CONTAINING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |