Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759590 | 0.97 | KMT2A (0.52) | SMN1; SMN2TSHRHTTCYP1A2CYP3A4 | |
| SCHEMBL8631402 | 0.91 | MAPT (0.57) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL8632208 | 0.84 | STAT3 (0.51) | SMN1; SMN2KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8632286 | 0.83 | KIT (0.45) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8632837 | 0.82 | LMNA (0.51) | CYP2C9CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL8632960 | 0.79 | KEAP1 (0.51) | SMN1; SMN2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8631178 | 0.79 | STAT3 (0.47) | TSHRHTTMEN1KMT2AMAPT | |
| SCHEMBL8627973 | 0.79 | KDM1A (0.51) | TSHRHTTMEN1KMT2AMAPT | |
| SCHEMBL8634763 | 0.79 | NAT1 (0.45) | SMN1; SMN2TSHRHTTMEN1KMT2A | |
| SCHEMBL8631560 | 0.79 | SLC40A1 (0.44) | MAPTKAT6AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |