SCHEMBL8632793

SCHEMBL8632793

CCCCOc1ccc(Oc2ccc(OCC=C(Br)Br)c(C(F)(F)F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.43
THRA P10827 2/20 0.40
THRB P10828 2/20 0.40
PPARG P37231 5/20 0.39
PPARA Q07869 3/20 0.39
ALOX5 P09917 2/20 0.39
PTGES O14684 1/20 0.39
S1PR1 P21453 3/20 0.39
PPARD Q03181 2/20 0.37
PSEN1 P49768 1/20 0.36
MAPK8 P45983 1/20 0.35
MAPK10 P53779 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
AR P10275 1/20 0.35
SPHK2 Q9NRA0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632120 0.95 LTA4H (0.43) LTA4HTHRATHRBPPARGPPARA
SCHEMBL8638264 0.91 LMNA (0.44) LTA4HMAPK8MAPK10LMNAMAPT
SCHEMBL8634546 0.89 S1PR1 (0.43) THRATHRBPPARGALOX5PTGES
SCHEMBL8635519 0.88 LTA4H (0.43) LTA4HTHRATHRBPPARGPPARA
SCHEMBL8637887 0.87 L3MBTL1 (0.39) LTA4HMAPK8MAPK10LMNAMAPT
SCHEMBL8632656 0.87 KDM4E (0.37) S1PR1LMNAAR
SCHEMBL8635188 0.86 S1PR1 (0.37) THRATHRBPPARGALOX5S1PR1
SCHEMBL8638939 0.85 SLC6A4 (0.41) LTA4HTHRBPPARGALOX5PPARD
SCHEMBL8635708 0.85 AR (0.39) THRATHRBPPARGPPARAALOX5
SCHEMBL8633959 0.85 MAPT (0.39) PPARGALOX5PSEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed