SCHEMBL8635519

SCHEMBL8635519

CCCCOc1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.43
PPARA Q07869 8/20 0.39
PPARG P37231 7/20 0.39
ALOX5 P09917 2/20 0.39
PTGES O14684 1/20 0.39
S1PR1 P21453 1/20 0.39
THRA P10827 2/20 0.38
THRB P10828 2/20 0.38
PPARD Q03181 5/20 0.37
HTT P42858 1/20 0.36
PSEN1 P49768 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635558 0.95 LTA4H (0.43) LTA4HPPARAPPARGALOX5PTGES
SCHEMBL8635048 0.91 MAPT (0.44) LTA4HHTT
SCHEMBL8635945 0.89 S1PR1 (0.43) PPARGALOX5PTGESS1PR1THRA
SCHEMBL8632793 0.88 LTA4H (0.43) LTA4HPPARAPPARGALOX5PTGES
SCHEMBL8633073 0.87 L3MBTL1 (0.39) HTT
SCHEMBL8636074 0.87 KDM4E (0.37) PPARAS1PR1HTT
SCHEMBL8635016 0.86 S1PR1 (0.37) PPARGALOX5S1PR1THRATHRB
SCHEMBL8636474 0.85 RXRA (0.38) LTA4HPPARGALOX5THRBPPARD
SCHEMBL8634174 0.85 AR (0.39) PPARAPPARGALOX5PPARDPSEN1
SCHEMBL8632518 0.85 MAPT (0.39) PPARGPPARDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed