SCHEMBL8633759

SCHEMBL8633759

Clc1ccc(Oc2cc(Cl)c(OCC=C(Br)Br)cc2Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 7/20 0.38
FFAR1 O14842 2/20 0.38
F2 P00734 1/20 0.38
F10 P00742 1/20 0.38
GCGR P47871 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MPO P05164 1/20 0.37
TPO P07202 1/20 0.37
EPX P11678 1/20 0.37
LPO P22079 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632796 0.87 TDP1 (0.41) FFAR1KDM4EMEN1ALDH1A1CYP1A2
SCHEMBL8633666 0.85 MPO (0.36) FFAR1F2F10CYP1A2CYP2D6
SCHEMBL8635751 0.79 HTT (0.46) PNLIPFFAR1F2F10MAPT
SCHEMBL8634719 0.79 PTGDR (0.34) PNLIPFFAR1
SCHEMBL8633165 0.77 TDP1 (0.37) ALDH1A1HTR2ASLC6A4
SCHEMBL8633455 0.77 PPARA (0.36) FFAR1MEN1ALDH1A1CYP1A2MAPT
SCHEMBL8632883 0.75 PPARD (0.39) FFAR1KDM4EHTR2ASLC6A4KCNH2
SCHEMBL8634588 0.74 SCN9A (0.35) ALDH1A1MAOAMAOB
SCHEMBL8635684 0.73 TDP1 (0.42) FFAR1KDM4EMEN1ALDH1A1CYP1A2
SCHEMBL8638737 0.73 HTR2A (0.43) HTR2ASLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed