Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634805 | 0.85 | TYK2 (0.48) | ALDH1A1HPGDRAB9ASMN1; SMN2JAK2 | |
| SCHEMBL8634357 | 0.85 | TYK2 (0.34) | JAK2JAK1TYK2KCNH2KIT | |
| SCHEMBL7761310 | 0.82 | SLC9A1 (0.62) | SLC9A1 | |
| SCHEMBL8632612 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8635344 | 0.81 | KMT2A (0.36) | SLC9A1ALDH1A1TYK2 | |
| SCHEMBL8635463 | 0.80 | AKR1C3 (0.45) | ALDH1A1 | |
| SCHEMBL8633035 | 0.79 | FDPS (0.33) | SLC9A1 | |
| SCHEMBL8635848 | 0.79 | CYP11B2 (0.46) | ALDH1A1 | |
| SCHEMBL8636232 | 0.78 | PTGS2 (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8631388 | 0.77 | GAA (0.40) | ALDH1A1SMN1; SMN2JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |