Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635463 | 0.87 | AKR1C3 (0.45) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8631102 | 0.86 | AKR1C3 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL8635848 | 0.85 | CYP11B2 (0.46) | KMT2AALDH1A1 | |
| SCHEMBL8634502 | 0.85 | PTGS1 (0.38) | KMT2APTGS1PTGS2ALDH1A1L3MBTL1 | |
| SCHEMBL8633408 | 0.85 | ALDH1A1 (0.39) | PTGS1PTGS2ALDH1A1 | |
| SCHEMBL8634356 | 0.84 | AKR1C3 (0.49) | KMT2A | |
| SCHEMBL8634936 | 0.82 | AKR1C3 (0.48) | KMT2AALDH1A1 | |
| SCHEMBL7768562 | 0.82 | SLC9A1 (0.61) | SLC9A1 | |
| SCHEMBL27526953 | 0.81 | RAPGEF4 (0.42) | KMT2AALDH1A1SLC9A1L3MBTL1 | |
| SCHEMBL8636256 | 0.81 | TBXA2R (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |