SCHEMBL863315

SCHEMBL863315

Cc1cc(-c2cccc(-c3ccc(F)cc3F)n2)[nH]n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 3/20 0.41
CTSA P10619 1/20 0.40
ALOX15 P16050 4/20 0.40
MAPT P10636 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
NFKB1 P19838 2/20 0.40
NFKB2 Q00653 2/20 0.40
RELA Q04206 2/20 0.40
CASP1 P29466 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
KMO O15229 1/20 0.38
TGFBR1 P36897 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20411750 0.86 ALPL (0.41) ALPLALOX15MAPTSMN1; SMN2MEN1
SCHEMBL867635 0.81 ABCC8 (0.38) ALPLCTSAALOX15MAPTSMN1; SMN2
SCHEMBL13261826 0.80 KMO (0.51) ALPLCTSAMEN1NPC1RAB9A
SCHEMBL15888380 0.79 CCR1 (0.52) CTSAMAPTKMOTGFBR1SCN9A
SCHEMBL23414256 0.77 PDE10A (0.45) ALPLALOX15MAPTSMN1; SMN2MEN1
SCHEMBL12322371 0.75 ALPL (0.36) ALPLCTSAALOX15MAPTSMN1; SMN2
SCHEMBL19625265 0.73 RAB9A (0.53) ALOX15MAPTSMN1; SMN2MEN1NPC1
SCHEMBL12958420 0.72 IDH1 (0.33) MEN1KMT2AHSP90AA1KDM4E
SCHEMBL9106265 0.72 KMO (0.45) ALPLCTSAMEN1NPC1RAB9A
SCHEMBL23414230 0.72 F2RL3 (0.35) ALPLALOX15MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS NATIONAL TSING HUA UNIVERSITY (TW) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS RUVBL2, RUVBL1, CCNL2 ALPL 2005/4885CTSA 4185/4885ALOX15 3534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.