Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635140 | 0.88 | BCAT2 (0.42) | MEN1KMT2AAKR1C3AKR1C2HPGD | |
| SCHEMBL8632359 | 0.87 | MEN1 (0.44) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL8633969 | 0.87 | CNR2 (0.43) | MEN1KMT2ALMNAAKR1C3AKR1C2 | |
| SCHEMBL8635252 | 0.86 | AKR1C3 (0.50) | MEN1KMT2ALMNASMN1; SMN2AKR1C3 | |
| SCHEMBL8635178 | 0.85 | AKR1C3 (0.48) | MEN1KMT2ALMNASMN1; SMN2AKR1C3 | |
| SCHEMBL7768698 | 0.85 | — | — | |
| SCHEMBL8632259 | 0.84 | YAP1 (0.49) | LMNAAKR1C3AKR1C2HPGDGAA | |
| SCHEMBL8632351 | 0.84 | PDE4B (0.41) | MEN1KMT2ALMNAHTTPTGS1 | |
| SCHEMBL8635462 | 0.82 | PDE4B (0.41) | SMN1; SMN2PTGS1PDE4BALDH1A1 | |
| SCHEMBL8634502 | 0.81 | PTGS1 (0.38) | KMT2ASMN1; SMN2PTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |