Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629124 | 0.89 | DRD4 (0.48) | DRD4DRD3DRD2HTR1AADRA1D | |
| SCHEMBL8631570 | 0.89 | MAPT (0.47) | RECQLDRD4DRD3P2RX7DRD2 | |
| SCHEMBL8629425 | 0.89 | DRD4 (0.56) | RECQLDRD4DRD3GRM2DRD2 | |
| SCHEMBL8631540 | 0.86 | KCNH2 (0.51) | RECQLDRD4DRD3DRD2HTR1A | |
| SCHEMBL8630582 | 0.86 | MAPT (0.54) | DRD4DRD2HTR1APOLBHSD17B10 | |
| SCHEMBL8633899 | 0.84 | KMT2A (0.50) | RECQLKMOADRA1DADRA1AADRA1B | |
| SCHEMBL8627836 | 0.83 | DRD4 (0.45) | RECQLDRD4DRD3P2RX7DRD2 | |
| SCHEMBL29520874 | 0.83 | RECQL (0.53) | RECQLP2RX7KMOPOLBHSD17B10 | |
| SCHEMBL8630535 | 0.83 | SIGMAR1 (0.53) | DRD3DRD2HTR1AADRA1AKCNH2 | |
| SCHEMBL8631008 | 0.82 | RECQL (0.67) | RECQLDRD4DRD3P2RX7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780475-A | Antipsychotic indazole derivatives | MERCK, SHARP & DOHME LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |