SCHEMBL8632792

SCHEMBL8632792

FC(F)(F)c1ccc(Oc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)c(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
SLC6A4 P31645 5/20 0.37
HTR2A P28223 4/20 0.37
KCNH2 Q12809 4/20 0.37
FFAR1 O14842 2/20 0.36
PTGDR2 Q9Y5Y4 3/20 0.35
THRB P10828 2/20 0.35
MRGPRX4 Q96LA9 4/20 0.34
HTT P42858 1/20 0.34
PPARD Q03181 1/20 0.34
THRA P10827 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633882 0.83 RXRA (0.39) RXRARXRBRXRGFFAR1PTGDR2
SCHEMBL8635191 0.83 CYP2C9 (0.41) THRA
SCHEMBL8632790 0.83 LMNA (0.46) PPARD
SCHEMBL8900222 0.82 TDP1 (0.36) FFAR1THRBMRGPRX4HTTTHRA
SCHEMBL8634571 0.81 THRB (0.39) RXRARXRBRXRGSLC6A4HTR2A
SCHEMBL8633492 0.81 FFAR1 (0.47) SLC6A4HTR2AKCNH2FFAR1MRGPRX4
SCHEMBL8635294 0.81 RAB9A (0.40) FFAR1HTT
SCHEMBL7965745 0.78 MAPT (0.35) HTT
SCHEMBL8408840 0.77 MAOB (0.42) MRGPRX4PPARD
SCHEMBL8633632 0.77 FFAR1 (0.51) SLC6A4HTR2AKCNH2FFAR1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed