Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632400 | 0.82 | MEN1 (0.39) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8701209 | 0.75 | L3MBTL1 (0.37) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8699754 | 0.74 | L3MBTL1 (0.36) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8630930 | 0.69 | SMN1; SMN2 (0.39) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8696712 | 0.67 | ESR1 (0.45) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL6670342 | 0.66 | CA12 (0.46) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8637224 | 0.64 | POLB (0.38) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8631456 | 0.64 | ALDH1A1 (0.56) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL171845 | 0.63 | MAPT (0.63) | KMT2AMEN1MAPTGAALMNA | |
| SCHEMBL18590696 | 0.63 | CHKA (0.67) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |