Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634739 | 0.82 | CA12 (0.41) | MEN1KMT2ALMNAMAPTCA12 | |
| SCHEMBL8699754 | 0.80 | L3MBTL1 (0.36) | MEN1KMT2ALMNARORCMAPT | |
| SCHEMBL8636968 | 0.67 | DRD4 (0.45) | RORCHTR1ADRD2 | |
| SCHEMBL8634075 | 0.65 | RORC (0.45) | RORC | |
| SCHEMBL3696561 | 0.64 | ALDH1A1 (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL6670342 | 0.62 | CA12 (0.46) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL7956788 | 0.61 | ITGB3 (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL6323362 | 0.61 | ITGB3 (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL7014542 | 0.61 | CNR2 (0.68) | MEN1KMT2ACNR1CNR2TSHR | |
| SCHEMBL8631456 | 0.60 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |