Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635203 | 0.88 | HSP90AA1 (0.35) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8634504 | 0.87 | FLT1 (0.38) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8633074 | 0.86 | CYP3A4 (0.37) | LMNAALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL8636231 | 0.86 | MCL1 (0.33) | LMNAALDH1A1MAPK1MAPT | |
| SCHEMBL8635329 | 0.85 | SLC9A1 (0.35) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27351468 | 0.84 | HRH4 (0.37) | — | |
| SCHEMBL8632126 | 0.84 | TUBB4A (0.37) | LMNAALDH1A1 | |
| SCHEMBL7761423 | 0.83 | SLC9A1 (0.45) | — | |
| SCHEMBL8631189 | 0.83 | MEN1 (0.31) | — | |
| SCHEMBL8634221 | 0.83 | SIRT2 (0.34) | SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |