Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635879 | 0.88 | MTNR1A (0.43) | ALDH1A1LMNA | |
| SCHEMBL8634504 | 0.87 | FLT1 (0.38) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL8636231 | 0.86 | MCL1 (0.33) | ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL8634267 | 0.86 | KEAP1 (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8635203 | 0.86 | HSP90AA1 (0.35) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL7768620 | 0.84 | SLC9A1 (0.44) | — | |
| SCHEMBL8635757 | 0.84 | SMN1; SMN2 (0.31) | ALDH1A1LMNA | |
| SCHEMBL8634221 | 0.83 | SIRT2 (0.34) | ALDH1A1LMNAPDK1PDK2PDK3 | |
| SCHEMBL8634165 | 0.82 | ESR1 (0.39) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL8633117 | 0.80 | PDE4B (0.40) | ALDH1A1USP2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |