Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635012 | 0.87 | NSD2 (0.36) | SLC9A1L3MBTL1RXRARXRBRXRG | |
| SCHEMBL8635629 | 0.86 | FLT1 (0.36) | SLC9A1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL8634555 | 0.86 | MKNK1 (0.38) | L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8635757 | 0.85 | SMN1; SMN2 (0.31) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8635192 | 0.85 | RXRA (0.35) | SLC9A1L3MBTL1RXRARXRBRXRG | |
| SCHEMBL8635732 | 0.84 | KCNJ6 (0.38) | — | |
| SCHEMBL8634267 | 0.83 | KEAP1 (0.41) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL7761267 | 0.82 | SLC9A1 (0.60) | SLC9A1 | |
| SCHEMBL8636116 | 0.82 | SLC9A1 (0.36) | SLC9A1 | |
| SCHEMBL8633950 | 0.82 | SIRT2 (0.35) | SLC9A1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |