Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631388 | 0.86 | GAA (0.40) | MAPTKCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL8634536 | 0.85 | CXCL8 (0.43) | PTGS2MEN1LMNAMAPTKMT2A | |
| SCHEMBL8635463 | 0.84 | AKR1C3 (0.45) | MEN1MAPTKMT2AAKR1C3ALDH1A1 | |
| SCHEMBL8635174 | 0.84 | AKR1C3 (0.49) | MEN1MAPTKMT2AAKR1C3PTGS1 | |
| SCHEMBL7768680 | 0.83 | SLC9A1 (0.60) | — | |
| SCHEMBL8630813 | 0.83 | AKR1C3 (0.50) | MEN1KMT2ACNR2PLA2G1BCYP1A2 | |
| SCHEMBL8633215 | 0.83 | L3MBTL1 (0.42) | MEN1LMNAMAPTKMT2AHPGD | |
| SCHEMBL8631102 | 0.81 | AKR1C3 (0.47) | MEN1LMNAMAPTKMT2ACNR2 | |
| SCHEMBL8635252 | 0.80 | AKR1C3 (0.50) | PTGS2MEN1LMNAMAPTKMT2A | |
| SCHEMBL8634805 | 0.79 | TYK2 (0.48) | MEN1LMNAMAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |