Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636232 | 0.86 | PTGS2 (0.40) | ALDH1A1KCNJ6KCNJ5KCNJ3IDH1 | |
| SCHEMBL8635172 | 0.85 | CXCL8 (0.42) | GAAALDH1A1ALOX15PKMCXCL8 | |
| SCHEMBL8630813 | 0.84 | AKR1C3 (0.50) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8635463 | 0.83 | AKR1C3 (0.45) | GAAALDH1A1ALOX15L3MBTL1POLB | |
| SCHEMBL8635174 | 0.83 | AKR1C3 (0.49) | GAAALDH1A1IDH1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7764107 | 0.82 | SLC9A1 (0.60) | — | |
| SCHEMBL8633215 | 0.82 | L3MBTL1 (0.42) | GAAALDH1A1ALOX15L3MBTL1POLB | |
| SCHEMBL8633408 | 0.81 | ALDH1A1 (0.39) | ALDH1A1IDH1SMN1; SMN2 | |
| SCHEMBL8632908 | 0.81 | PTGS1 (0.43) | GAAKCNJ6KCNJ5KCNJ3IDH1 | |
| SCHEMBL8634805 | 0.78 | TYK2 (0.48) | GAAALDH1A1JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057999-C | 4-Aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| US-5739142-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-14 | — | — | US | disclosed |
| CN-1138575-A | 4-aminobenzoylguanidine derivatives | MERCK PATENT GMBH (DE) | 1996-12-25 | — | — | CN | disclosed |