Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 18/20 | 0.43 |
| ▸ | EDNRB | P24530 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635722 | 0.93 | DHPS (0.35) | DHPSEDNRAEDNRB | |
| SCHEMBL8635760 | 0.89 | DHPS (0.50) | DHPSEDNRAEDNRB | |
| SCHEMBL8631708 | 0.81 | DHPS (0.42) | DHPSEDNRAEDNRB | |
| SCHEMBL7850977 | 0.77 | DHPS (0.65) | DHPS | |
| SCHEMBL8638012 | 0.73 | DHPS (0.39) | DHPSEDNRAEDNRB | |
| SCHEMBL8395334 | 0.73 | LMNA (0.37) | DHPSEDNRAEDNRB | |
| SCHEMBL7852059 | 0.72 | EDNRA (0.65) | DHPSEDNRAEDNRB | |
| SCHEMBL31037804 | 0.68 | DHPS (0.66) | DHPS | |
| SCHEMBL7851037 | 0.68 | DHPS (0.52) | DHPS | |
| SCHEMBL6785297 | 0.68 | EDNRA (0.66) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837708-A | CARDIOVASCULAR DISORDERS OF HYPERTENSION, ISCHEMIA, ANGINA PECTORIS AND VASOSPASMS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |