Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652108 | 0.86 | L3MBTL1 (0.50) | L3MBTL1NPC1TDP1LMNAALDH1A1 | |
| SCHEMBL8650136 | 0.82 | TDP1 (0.51) | L3MBTL1NPC1TDP1LMNAALDH1A1 | |
| SCHEMBL8646855 | 0.79 | PTGS2 (0.59) | LMNAALDH1A1SMN1; SMN2RAB9AHTT | |
| SCHEMBL11227892 | 0.76 | LMNA (0.64) | L3MBTL1LMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29936785 | 0.75 | L3MBTL1 (0.49) | L3MBTL1NPC1TDP1LMNAALDH1A1 | |
| SCHEMBL8652111 | 0.74 | MAPT (0.50) | L3MBTL1LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL19397824 | 0.73 | FGFR1 (0.56) | TDP1LMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6465316 | 0.72 | ALDH1A1 (0.73) | L3MBTL1NPC1TDP1LMNAALDH1A1 | |
| SCHEMBL6441497 | 0.72 | ALDH1A1 (0.53) | L3MBTL1NPC1TDP1LMNAALDH1A1 | |
| Bicarbonate SCHEMBL29125500 | 0.72 | PTGS2 (0.60) | L3MBTL1NPC1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843999-A | 2-phenylazulene derivatives and a manufacturing method of these compounds | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |