Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TK2 | O00142 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662934 | 0.84 | SLC6A1 (0.33) | SLC6A1SLC6A11HTT | |
| SCHEMBL8661014 | 0.83 | MAPT (0.38) | MEN1MAPTKMT2ACHRM3 | |
| SCHEMBL8660375 | 0.79 | SLC6A1 (0.36) | SMN1; SMN2SLC6A1MEN1KMT2ASLC6A11 | |
| SCHEMBL8659948 | 0.78 | TSHR (0.35) | TSHRSLC6A1MEN1KMT2ASLC6A11 | |
| SCHEMBL8662709 | 0.76 | MTNR1B (0.37) | TP53ALOX15TSHRMAPK1SLC6A1 | |
| SCHEMBL8662093 | 0.76 | PIK3CD (0.35) | SMN1; SMN2SLC6A1MEN1KMT2ASLC6A11 | |
| SCHEMBL8661342 | 0.76 | ALDH1A1 (0.35) | CYP3A4SMN1; SMN2SLC6A1MEN1GAA | |
| SCHEMBL6858148 | 0.75 | ITGA4 (0.39) | TP53ALOX15MEN1KMT2A | |
| SCHEMBL8661541 | 0.75 | SLC6A1 (0.34) | TP53ALOX15TSHRMAPK1SLC6A1 | |
| SCHEMBL8661019 | 0.74 | LMNA (0.38) | MAPTDRD2OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714606-A | OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |