Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662717 | 0.92 | MTNR1B (0.37) | MTNR1BSLC6A1RIPK1ITGB2ICAM1 | |
| SCHEMBL8660375 | 0.88 | SLC6A1 (0.36) | MTNR1BSLC6A1RIPK1ITGB2ICAM1 | |
| SCHEMBL8662093 | 0.86 | PIK3CD (0.35) | SLC6A1RIPK1ITGB2ICAM1ITGAL | |
| SCHEMBL15592424 | 0.86 | SLC6A11 (0.45) | SLC6A1RIPK1LMNAKDM4EMEN1 | |
| SCHEMBL6858148 | 0.85 | ITGA4 (0.39) | RBP4ITGA4LMNAKDM4EMEN1 | |
| SCHEMBL8660410 | 0.84 | POLB (0.44) | LMNAKDM4EMEN1TP53POLB | |
| SCHEMBL8661342 | 0.82 | ALDH1A1 (0.35) | SLC6A1HTTLMNAMEN1POLB | |
| SCHEMBL8662809 | 0.82 | CYP2D6 (0.37) | SLC6A1RIPK1ITGB2ICAM1ITGAL | |
| SCHEMBL8662486 | 0.82 | MTNR1B (0.40) | MTNR1BMEN1KMT2A | |
| SCHEMBL8662934 | 0.82 | SLC6A1 (0.33) | SLC6A1RIPK1ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714606-A | OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |