SCHEMBL8661389

SCHEMBL8661389

CON1C(=O)CCC(=O)[C@]1(C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)c1ccc[c]c1[N+](=O)[O-])C(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 18/20 0.36
CMA1 P23946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL387694 0.82 TACR1 (0.40) ELANECMA1
SCHEMBL2289363 0.81 ELANE (0.42) ELANECMA1
SCHEMBL3276266 0.78 ELANE (0.42) ELANECMA1
SCHEMBL228960 0.78 ELANE (0.38) ELANECMA1
SCHEMBL8662040 0.78 ELANE (0.40) ELANECMA1
SCHEMBL5487413 0.78 ELANE (0.38) ELANECMA1
SCHEMBL398010 0.77 KCNH2 (0.39)
SCHEMBL5494650 0.76 ELANE (0.40) ELANECMA1
SCHEMBL535732 0.75 ACE (0.40)
SCHEMBL846697 0.74 FKBP4 (0.51) CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776780-A AUTOMATIC ANALYZING; COLORIMETRIC PHOTOMETRY CHIMERA RESEARCH & CHEMICAL, INC. (US) 1998-07-07 US claimed
US-5776780-A AUTOMATIC ANALYZING; COLORIMETRIC PHOTOMETRY CHIMERA RESEARCH & CHEMICAL, INC. (US) 1998-07-07 US disclosed