Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.35 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664792 | 0.88 | SETDB1 (0.42) | SETDB1ALDH1A1PTGER1UCHL1UCHL3 | |
| SCHEMBL8663188 | 0.87 | ALDH1A1 (0.42) | SETDB1ALDH1A1SMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL8667576 | 0.83 | ALDH1A1 (0.39) | SETDB1ALDH1A1SMN1; SMN2CYP2C19CYP2C9 | |
| SCHEMBL8675983 | 0.81 | SETDB1 (0.38) | SETDB1ALDH1A1PTGER1CASP2CUL4A | |
| SCHEMBL23712860 | 0.72 | P2RX7 (0.35) | CASP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28049660 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP1A2MEN1KMT2A | |
| SCHEMBL8670561 | 0.69 | DDR1 (0.35) | SETDB1ALDH1A1SMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL21713935 | 0.68 | FFAR4 (0.44) | SETDB1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8664609 | 0.67 | SETDB1 (0.37) | SETDB1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18498771 | 0.67 | KDM4E (0.43) | ALDH1A1SMN1; SMN2CYP2C19CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874831-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019935-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |