SCHEMBL866475

SCHEMBL866475

C=C(OCC)C1(C)COC(=O)OC1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.45
ALOX15 P16050 2/20 0.31
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TSHR P16473 1/20 0.30
POLB P06746 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19567960 0.83 PRKCA (0.36) ATML3MBTL1TSHRPOLB
SCHEMBL10294950 0.81 ATM (0.33) ATMTSHR
SCHEMBL15198822 0.80 ATM (0.32) ATM
SCHEMBL663919 0.80 ATM (0.50) ATMALOX15KMT2AL3MBTL1TSHR
SCHEMBL16417655 0.80 ALDH1A1 (0.42) KMT2AL3MBTL1MEN1
SCHEMBL10295054 0.79 ATM (0.31) ATM
SCHEMBL16417656 0.78 SMN1; SMN2 (0.31) ATM
SCHEMBL16625635 0.76 ATM (0.31) ATM
SCHEMBL20110278 0.75 ATM (0.39) ATMALOX15
SCHEMBL19567945 0.73 ALOX5 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-9999633-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-19 US disclosed
US-9987369-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-05 US disclosed
US-20180117162-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-05-03 US disclosed
US-9854806-B2 Antimicrobial guanidinium and thiouronium functionalized polymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-01-02 US disclosed
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-26 US disclosed
US-9637592-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-05-02 US disclosed
US-9631050-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-04-25 US disclosed
US-20170051105-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-02-23 US disclosed
US-9511146-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-12-06 US disclosed
US-20150098976-A1 ANTIMICROBIAL AND ANTIFOULING CATECHOL-CONTAINING POLYCARBONATES FOR MEDICAL APPLICATIONS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-04-09 US disclosed
US-8962772-B2 Antimicrobial surface modified silicone rubber and methods of preparation thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-02-24 US disclosed
US-8940855-B2 Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-01-27 US disclosed
US-20140301970-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-10-09 US disclosed
US-20140301968-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-10-09 US disclosed
US-20140301967-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-10-09 US disclosed
US-20130217853-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-08-22 US disclosed
US-8450505-B2 Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-05-28 US disclosed
US-20120172603-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 US disclosed
US-20120172559-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172603-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA ATM 3376/4885ALOX15 1362/4885KMT2A 4165/4885
US-20140301967-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES VDR, GC, CYP24A1 ATM 4846/4885ALOX15 1251/4885KMT2A 3944/4885
US-20170051105-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS VDR, PROC, CYP24A1 ATM 4871/4885ALOX15 2247/4885KMT2A 3993/4885
US-20170303541-A1 ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS PUF60, CAPG, GMPS ATM 3036/4885ALOX15 4810/4885KMT2A 4588/4885
US-20140301968-A1 ANTIMICROBIAL CATIONIC POLYCARBONATES VDR, GC, CYP24A1 ATM 4846/4885ALOX15 1251/4885KMT2A 3944/4885
US-20180117162-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS VDR, PROC, CYP24A1 ATM 4874/4885ALOX15 1848/4885KMT2A 4014/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS ATM 3036/4885ALOX15 4810/4885KMT2A 4588/4885
US-20140301970-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS VDR, PROC, CYP24A1 ATM 4871/4885ALOX15 2247/4885KMT2A 3993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.