Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.37 |
| ▸ | FPR2 | P25090 | 10/20 | 0.36 |
| ▸ | FPR1 | P21462 | 9/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668018 | 0.90 | MAPT (0.39) | FPR2FPR1HTR1A | |
| SCHEMBL8485533 | 0.85 | NPSR1 (0.42) | — | |
| SCHEMBL8665880 | 0.84 | UTS2R (0.39) | — | |
| SCHEMBL8501233 | 0.83 | NPSR1 (0.36) | KCNH2 | |
| SCHEMBL8484454 | 0.83 | NPSR1 (0.42) | — | |
| SCHEMBL8666092 | 0.82 | UTS2R (0.39) | — | |
| SCHEMBL8501048 | 0.81 | NPSR1 (0.35) | KCNH2 | |
| SCHEMBL8500996 | 0.79 | CTSL (0.37) | — | |
| SCHEMBL8665495 | 0.78 | CCR2 (0.35) | CCR2KCNH2CCR5 | |
| SCHEMBL8593677 | 0.78 | ALDH1A1 (0.36) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | claimed |