Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490734 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL491053 | 0.80 | ALDH1A1 (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL2519476 | 0.80 | MAOA (0.37) | ALDH1A1MAPT | |
| SCHEMBL14973574 | 0.79 | NPC1 (0.41) | CHRM1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3761239 | 0.79 | PTGS2 (0.43) | PTGS2CHRM1NPC1RAB9AMEN1 | |
| SCHEMBL490735 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9AKMT2AALDH1A1CYP1A2 | |
| SCHEMBL5554839 | 0.76 | ALDH1A1 (0.48) | CHRM1NPC1RAB9AALDH1A1 | |
| SCHEMBL8664748 | 0.76 | CYP1A2 (0.48) | CHRM1NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL490744 | 0.76 | NPY5R (0.44) | NPC1MEN1KMT2AGAAALDH1A3 | |
| SCHEMBL150156 | 0.75 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |