Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668653 | 0.80 | HTT (0.40) | ALOX5SIRT2SIRT1KDM4ELMNA | |
| SCHEMBL5810875 | 0.72 | ALDH1A1 (0.41) | ALOX5LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL28819182 | 0.68 | ALDH1A1 (0.54) | ALOX5KDM4ELMNAALDH1A1TUBB4A | |
| SCHEMBL5808515 | 0.68 | PTGS2 (0.39) | ALOX5ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL5643293 | 0.66 | ALDH1A1 (0.65) | KDM4ELMNAALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8675620 | 0.66 | TUBB4A (0.36) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8646870 | 0.64 | HSP90AA1 (0.34) | LMNAALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL8891252 | 0.64 | HTT (0.43) | ALOX5LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11001722 | 0.63 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL5809994 | 0.63 | L3MBTL1 (0.44) | ALOX5KDM4ELMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |