Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666222 | 0.81 | SIGMAR1 (0.40) | FKBP1AKDM1AADAM10ERBB2MMP2 | |
| SCHEMBL8668993 | 0.78 | TSHR (0.44) | ALDH1A1SMN1; SMN2USP2HPGDHSD17B10 | |
| SCHEMBL8667689 | 0.78 | GPR88 (0.35) | KDM4EALDH1A1USP2MEN1KMT2A | |
| SCHEMBL8669414 | 0.77 | SIGMAR1 (0.43) | — | |
| SCHEMBL8672106 | 0.75 | LMNA (0.37) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8670326 | 0.73 | AGTR2 (0.34) | KDM4EKDM1AALDH1A1NPC1RAB9A | |
| SCHEMBL8666883 | 0.73 | AGTR2 (0.34) | KDM4EKDM1AALDH1A1NPC1RAB9A | |
| SCHEMBL8672929 | 0.71 | KMT2A (0.39) | KDM4EALDH1A1SMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL8666332 | 0.70 | ACE (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8671381 | 0.70 | EPHX2 (0.34) | KDM4EKDM1AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |