Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525020 | 0.84 | ALDH1A1 (0.46) | AKR1C3AKR1C1ALDH1A1LMNAMAPT | |
| SCHEMBL35218 | 0.84 | ALDH1A1 (0.46) | AKR1C3AKR1C1ALDH1A1LMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL15575570 | 0.83 | ALDH1A1 (0.45) | AKR1C3AKR1C1ALDH1A1LMNAMAPT | |
| SCHEMBL726937 | 0.72 | TSHR (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL6888383 | 0.72 | LMNA (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9822576 | 0.72 | TDP1 (0.61) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6724747 | 0.71 | TSHR (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL35030 | 0.71 | F2 (0.57) | AKR1C3AKR1C1ALDH1A1MAPT | |
| SCHEMBL29792725 | 0.71 | F2 (0.57) | AKR1C3AKR1C1ALDH1A1MAPT | |
| SCHEMBL30901132 | 0.70 | CA2 (0.46) | AKR1C3AKR1C1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |