Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022907 | 0.83 | MMP1 (0.49) | KMT2ALMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8183471 | 0.79 | MMP1 (0.39) | KMT2AALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL8189340 | 0.78 | FFAR1 (0.51) | — | |
| SCHEMBL8672805 | 0.78 | ENPP3 (0.47) | — | |
| SCHEMBL8173385 | 0.77 | PYGL (0.47) | KMT2ALMNAALDH1A1HTTGAA | |
| SCHEMBL8187216 | 0.77 | L3MBTL1 (0.50) | KMT2APOLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8670338 | 0.77 | LMNA (0.41) | KMT2APOLBLMNAALDH1A1MEN1 | |
| SCHEMBL8182917 | 0.76 | PYGL (0.46) | KMT2APOLBLMNAALDH1A1MEN1 | |
| SCHEMBL8670131 | 0.75 | TLR7 (0.38) | KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1387707 | 0.74 | P2RY1 (0.45) | KMT2APOLBLMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776951-A | ANTICHOLESTEROL AGENT | GLAXO WELLCOME INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0706508-A1 | ANTI-ATHEROSCLEROTIC DIARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001326-A1 | ANTI-ATHEROSCLEROTIC DIARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-01-12 | — | — | WO | disclosed |