SCHEMBL8675833

SCHEMBL8675833

C=C(C)C(=O)OCCOC(=O)NC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.57
APEX1 P27695 2/20 0.52
LMNA P02545 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TSHR P16473 3/20 0.50
CHRNB2 P17787 2/20 0.48
CHRNA4 P43681 2/20 0.48
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM5 P08912 1/20 0.48
CYP2D6 P10635 1/20 0.48
CHRM1 P11229 1/20 0.48
NFKB1 P19838 1/20 0.48
CHRM3 P20309 1/20 0.48
MAPK1 P28482 1/20 0.48
CHRNA7 P36544 1/20 0.48
EPHX1 P07099 2/20 0.47
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21483474 0.90 TSHR (0.65) THRBAPEX1LMNASMN1; SMN2TSHR
SCHEMBL15636 0.84 THRB (0.74) THRBAPEX1LMNASMN1; SMN2TSHR
SCHEMBL6142874 0.84 THRB (0.74) THRBAPEX1LMNASMN1; SMN2TSHR
SCHEMBL13060038 0.83 CHRNB2 (0.48) THRBAPEX1LMNASMN1; SMN2TSHR
SCHEMBL21117173 0.83 THRB (0.57) THRBAPEX1LMNASMN1; SMN2TSHR
SCHEMBL11544013 0.83 TSHR (0.45) THRBAPEX1LMNASMN1; SMN2TSHR
Ethylene SCHEMBL2367613 0.82 THRB (0.71) THRBAPEX1LMNASMN1; SMN2TSHR
Ethylene SCHEMBL955493 0.82 THRB (0.71) THRBAPEX1LMNASMN1; SMN2TSHR
Ethylene SCHEMBL632736 0.82 THRB (0.71) THRBAPEX1LMNASMN1; SMN2TSHR
Ethylene SCHEMBL619217 0.82 THRB (0.71) THRBAPEX1LMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787878-B2 Photocurable compositions for stereolithography, method of forming the compositions, stereolithography methods using the compositions, polymer components formed by the stereolithography methods, and a device including the polymer components ROGERS CORPORATION (US) 2023-10-17 US disclosed
US-11753530-B2 Inter-penetrating elastomer network derived from ground tire rubber particles COE WILLIAM B (US) 2023-09-12 US disclosed
US-10781166-B2 Biocompositions for 3D printing 3D-BIOMATERIALS, LLC (US) 2020-09-22 US disclosed
US-10689521-B2 Low density UV-curable optical fiber coating, fiber made therewith, and method of fiber manufacture OFS FITEL, LLC (US) 2020-06-23 US disclosed
US-20190194123-A1 BIOCOMPOSITIONS FOR 3D PRINTING 3D - BIOMATERIALS, LLC 2019-06-27 US disclosed
US-20180044501-A1 METHOD FOR MAKING COLORED FILM, COLORED FILM, COLORED MATERIAL, AND OPHTHALMIC LENS SCIENBIZIP CONSULTING(SHENZHEN)CO.,LTD. (CN) 2018-02-15 US disclosed
US-20160280807-A1 PREPARATION OF NON-ISOCYANATE URETHANE (METH) ACRYLATES FOR URETHANE FUNCTIONAL LATEX THE UNIVERSITY OF AKRON 2016-09-29 US disclosed
US-20160280807-A1 PREPARATION OF NON-ISOCYANATE URETHANE (METH) ACRYLATES FOR URETHANE FUNCTIONAL LATEX THE UNIVERSITY OF AKRON 2016-09-29 US disclosed
US-20160280807-A1 PREPARATION OF NON-ISOCYANATE URETHANE (METH) ACRYLATES FOR URETHANE FUNCTIONAL LATEX THE UNIVERSITY OF AKRON 2016-09-29 US disclosed
EP-2346910-B1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI DENTAL DIVISION (US) 2016-07-13 EP disclosed
US-8727775-B2 Dimer acid-derived dimethacrylates and use in dental restorative compositions THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2014-05-20 US disclosed
US-8513326-B2 Carbamate-methacrylate monomers and their use in dental applications SEPTODONT CONFI-DENTAL (US) 2013-08-20 US disclosed
US-20110020751-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-7868059-B2 Polymerizable dye-monomer conjugates for encapsulating pigment particles HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-01-11 US disclosed
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-12-09 US disclosed
WO-2010042818-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-04-15 WO disclosed
US-20090025601-A1 POLYMERIZABLE DYE-MONOMER CONJUGATES FOR ENCAPSULATING PIGMENT PARTICLES HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2009-01-29 US disclosed
US-5840806-A COMPOSITION COMPRISING RESIN FORMED BY CONDENSATION OF POLYSILOXANE WITH POLYMER HAVING HYDROLYZABLE SILYL GROUP AND ADDITIONAL FUNCTIONAL GROUP, COMPOUND CAPABLE OF REACTING WITH SAID GROUP DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-11-24 US disclosed
US-5576406-A ACRYLATE POLYMERS FOR PAINTS, ADHESIVES OR SEALS DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-11-19 US disclosed
US-4165266-A LIQUID MONOACRYLATE MONOMER AND A POLYVINYL ALKYL ETHER, QUICK STICKING UNION CARBIDE CORPORATION (US) 1979-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194123-A1 BIOCOMPOSITIONS FOR 3D PRINTING HTR3D, ILK, ITGB3 THRB 4743/4885APEX1 3988/4885LMNA 3586/4885
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS CAD, ACMSD, MMAB THRB 4415/4885APEX1 821/4885LMNA 1883/4885
US-20160280807-A1 PREPARATION OF NON-ISOCYANATE URETHANE (METH) ACRYLATES FOR URETHANE FUNCTIONAL LATEX ACR, MUS81, ALG3 THRB 1879/4885APEX1 1268/4885LMNA 2149/4885
US-10781166-B2 Biocompositions for 3D printing HTR3D, ILK, ITGB3 THRB 4743/4885APEX1 3988/4885LMNA 3586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.