Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GPR183 | P32249 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699812 | 0.85 | CES2 (0.47) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7664334 | 0.79 | ADAMTS5 (0.52) | KMT2AMEN1GPR183ALDH1A1ADAMTS5 | |
| SCHEMBL105460 | 0.79 | ATF4 (0.54) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL8698847 | 0.77 | PPARG (0.50) | KMT2AMEN1GPR183ADAMTS5L3MBTL1 | |
| SCHEMBL3054083 | 0.75 | PLA2G4B (0.64) | KMT2AMEN1L3MBTL1MAPTCYP1A2 | |
| SCHEMBL3299784 | 0.75 | NPC1 (0.62) | ALDH1A1L3MBTL1MAPTTDP1NPC1 | |
| SCHEMBL11459201 | 0.75 | LMNA (0.56) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9362390 | 0.74 | ATF4 (0.50) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL10760471 | 0.74 | USP2 (0.50) | KMT2AMEN1GPR183ALDH1A1ADAMTS5 | |
| SCHEMBL10760470 | 0.74 | USP2 (0.50) | KMT2AMEN1GPR183ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |