Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681041 | 0.98 | L3MBTL1 (0.32) | L3MBTL1USP2ALOX15TSHRPOLB | |
| SCHEMBL8704127 | 0.86 | L3MBTL1 (0.33) | L3MBTL1USP2ALOX15TSHRMEN1 | |
| SCHEMBL8686156 | 0.84 | SLC6A3 (0.33) | L3MBTL1 | |
| SCHEMBL8706192 | 0.84 | HPGD (0.32) | L3MBTL1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL8682180 | 0.81 | KDM4E (0.30) | L3MBTL1HPGD | |
| SCHEMBL8680858 | 0.81 | FAAH (0.39) | L3MBTL1NPSR1MEN1KMT2ATDP1 | |
| SCHEMBL8707808 | 0.81 | PRKCA (0.37) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL8683191 | 0.81 | FAAH (0.46) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL8682103 | 0.81 | FAAH (0.46) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL8681078 | 0.81 | FAAH (0.46) | L3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0844000-A1 | Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis | SANKYO COMPANY LIMITED (JP) | 1998-05-27 | — | — | EP | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0600717-A1 | Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis | SANKYO COMPANY LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |