Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698196 | 0.91 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL17580458 | 0.89 | ALDH1A1 (0.47) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL3990674 | 0.89 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29595940 | 0.89 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL14247146 | 0.87 | MAPT (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL8095561 | 0.87 | MAPT (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30110723 | 0.84 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL564506 | 0.84 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL45486 | 0.84 | TDP1 (0.60) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL9821008 | 0.82 | MAPT (0.49) | TDP1ATMALDH1A1HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12485169-B2 | Compounds | Grey Wolf Therapeutics Limited (GB) | 2025-12-02 | — | — | US | disclosed |
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-07-17 | — | — | US | disclosed |
| CN-120025279-A | Compounds capable of modulating endoplasmic reticulum aminopeptidase 1 | 格雷沃尔夫治疗有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20250136576-A1 | Heterocyclic Compounds and Uses Thereof | ACEA Therapeutics, Inc. (US) | 2025-05-01 | — | — | US | disclosed |
| US-20240376046-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2024-11-14 | — | — | US | disclosed |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2024-11-07 | — | — | US | disclosed |
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-4376955-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| EP-4370212-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| US-7115644-B2 | Heterocyclic compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-10-03 | — | — | US | disclosed |
| EP-1539708-A1 | BENZIMIDAZOLONES AND THEIR USE AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040192748-A1 | Heterocyclic compounds | BOEHRINGER INGELHEIM PARMACEUTICALS, INC. | 2004-09-30 | — | — | US | disclosed |
| WO-2004024699-A1 | BENZIMIDAZOLONES AND THEIR USE AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-03-25 | — | — | WO | disclosed |
| US-6121265-A | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| CN-1036564-C | Herbicidal glutarmides | ROHM & HAAS (US) | 1997-12-03 | — | — | CN | disclosed |
| EP-0783506-A1 | NEW HETEROCYCLIC SUBSTITUTED IMIDAZOLOQUINOXALINONES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010572-A1 | NEW HETEROCYCLIC SUBSTITUTED IMIDAZOLOQUINOXALINONES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | disclosed |
| EP-0413832-A1 | OXAZOLIDINEDIONE DERIVATIVES AND PRODUCTION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0379894-A2 | Process for the preparation of (5-fluoro-2-nitro-4-heterocyclylphenoxy)-acetic-acid derivatives, and intermediates | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192748-A1 | Heterocyclic compounds | IL1B, CCL5, IL4 | TDP1 3963/4885ATM 1641/4885ALDH1A1 158/4885 |
| US-20240368150-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | BICRA, BRD4, CNR1 | TDP1 2609/4885ATM 2708/4885ALDH1A1 1572/4885 |
| US-12485169-B2 | Compounds | SLC10A1, VHL, CFTR | TDP1 1403/4885ATM 991/4885ALDH1A1 276/4885 |
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | TDP1 683/4885ATM 1965/4885ALDH1A1 443/4885 |
| US-20240376046-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | ERAP1, XPO1, RRP15 | TDP1 4154/4885ATM 4085/4885ALDH1A1 2435/4885 |
| US-20250136576-A1 | Heterocyclic Compounds and Uses Thereof | CHEK2, CDK2, CDK1 | TDP1 1561/4885ATM 290/4885ALDH1A1 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.