Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28305619 | 0.83 | OGG1 (0.51) | POLBOGG1BCHEPKMMEN1 | |
| SCHEMBL28062873 | 0.81 | RIPK1 (0.49) | POLBOGG1BCHEPKMKDM4E | |
| SCHEMBL6442574 | 0.78 | ELANE (0.53) | KMT2AELANE | |
| Hydrochloric Acid SCHEMBL8790691 | 0.77 | ELANE (0.51) | ELANE | |
| SCHEMBL337714 | 0.77 | CYP3A4 (0.63) | OGG1BCHEMEN1KMT2AKDM4E | |
| SCHEMBL4344418 | 0.77 | MEN1 (0.73) | POLBOGG1BCHEMEN1KMT2A | |
| SCHEMBL5916715 | 0.76 | BCHE (0.51) | OGG1BCHEMEN1KMT2AKDM4E | |
| SCHEMBL7932475 | 0.76 | BCHE (0.51) | OGG1BCHEMEN1KMT2AKDM4E | |
| SCHEMBL24901075 | 0.75 | BCHE (0.43) | POLBOGG1BCHEMEN1KMT2A | |
| SCHEMBL11798709 | 0.75 | FAAH (0.49) | POLBOGG1BCHEKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767088-A | USEFUL FOR TREATING PAIN, INFLAMMATION, SMOOTH MUSCLE CONTRACTION AND INDUCING VASODILATION | WARNER-LAMBERT COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| US-5610145-A | CARBAMATE STEREOISOMERS | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0755404-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028418-A2 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-10-26 | — | — | WO | disclosed |