Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590457 | 0.89 | MAPK1 (0.48) | SLC40A1KMT2AMEN1CA1CA2 | |
| SCHEMBL8703196 | 0.80 | MAPK1 (0.58) | SLC40A1KMT2AMEN1CA1CA2 | |
| SCHEMBL51046 | 0.73 | MAPK1 (0.68) | SLC40A1KMT2AMEN1CA1CA2 | |
| SCHEMBL29663898 | 0.73 | MAPK1 (0.68) | SLC40A1KMT2AMEN1CA1CA2 | |
| SCHEMBL3649176 | 0.68 | KDM4E (0.45) | CNR1GAAALDH1A1KDM4E | |
| SCHEMBL6894312 | 0.67 | GLO1 (0.61) | SLC40A1KMT2AMEN1CA1CA2 | |
| SCHEMBL8734368 | 0.67 | ALDH1A1 (0.55) | KMT2AMEN1CA1CA2MAPK1 | |
| SCHEMBL28490306 | 0.67 | GAA (0.51) | SLC40A1KMT2AMEN1CA1CA2 | |
| SCHEMBL3649719 | 0.66 | FBP1 (0.38) | KMT2AMEN1CNR1CA1CA2 | |
| SCHEMBL14919762 | 0.66 | MEN1 (0.73) | SLC40A1KMT2AMEN1ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |