Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710444 | 1.00 | BCHE (0.39) | BCHEACHEKMT2AMAPTLMNA | |
| SCHEMBL8292466 | 0.78 | KMT2A (0.33) | BCHEACHEKMT2AMAPTLMNA | |
| SCHEMBL7460807 | 0.74 | ALOX5 (0.36) | MAPTALDH1A1SMN1; SMN2HTTMAPK1 | |
| SCHEMBL7055976 | 0.74 | CYP11B1 (0.33) | ACHELMNATSHRALDH1A1 | |
| SCHEMBL5548677 | 0.74 | LMNA (0.36) | BCHEACHEKMT2ALMNAMEN1 | |
| SCHEMBL6066254 | 0.73 | ALDH1A1 (0.31) | LMNAALDH1A1 | |
| SCHEMBL7053946 | 0.72 | CYP19A1 (0.32) | LMNAALDH1A1 | |
| SCHEMBL61361 | 0.72 | CYP19A1 (0.32) | LMNAALDH1A1 | |
| SCHEMBL29844183 | 0.72 | CYP19A1 (0.32) | LMNAALDH1A1 | |
| SCHEMBL3811480 | 0.72 | ALDH1A1 (0.30) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874860-A1 | SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997015583-A1 | SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1997-05-01 | — | — | WO | disclosed |