Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719246 | 0.89 | ATM (0.40) | MAPK1NR3C1NR3C2CASRKMT2A | |
| SCHEMBL8720032 | 0.85 | KDM4E (0.40) | LMNANR3C1NR3C2KMT2AMEN1 | |
| SCHEMBL8718953 | 0.83 | STAT3 (0.41) | LMNANR3C1CASRKMT2AMEN1 | |
| SCHEMBL8713610 | 0.83 | LMNA (0.43) | LMNANR3C1NR3C2CASRPGR | |
| SCHEMBL8716671 | 0.81 | ADRB2 (0.40) | LMNAKMT2AMEN1ATMSTAT3 | |
| SCHEMBL8713354 | 0.81 | ALOX15 (0.40) | KMT2AMEN1ATMSTAT3ALDH1A1 | |
| SCHEMBL8433303 | 0.79 | MEN1 (0.39) | LMNANR3C1CASRKMT2AMEN1 | |
| SCHEMBL8433905 | 0.79 | MEN1 (0.39) | LMNANR3C1CASRKMT2AMEN1 | |
| SCHEMBL8718432 | 0.78 | LMNA (0.40) | LMNAMAPK1KMT2AMEN1ATM | |
| SCHEMBL8713922 | 0.78 | LMNA (0.49) | LMNAKMT2AMEN1ATMSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |