Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715434 | 1.00 | SIGMAR1 (0.51) | SIGMAR1LDHAADRB2ALDH1A1LMNA | |
| SCHEMBL8714129 | 0.90 | LDHA (0.48) | SIGMAR1LDHAADRB2ALDH1A1LMNA | |
| SCHEMBL8714130 | 0.90 | LDHA (0.48) | SIGMAR1LDHAADRB2ALDH1A1LMNA | |
| SCHEMBL8713854 | 0.83 | ALOX15 (0.53) | SIGMAR1LDHAADRB2ALDH1A1LMNA | |
| SCHEMBL8713857 | 0.83 | ALOX15 (0.53) | SIGMAR1LDHAADRB2ALDH1A1LMNA | |
| SCHEMBL8713241 | 0.78 | PPARG (0.43) | LDHAADRB2 | |
| SCHEMBL8713237 | 0.78 | PPARG (0.43) | LDHAADRB2 | |
| SCHEMBL10028825 | 0.76 | ADRB2 (0.66) | LDHAADRB2ALDH1A1LMNASTAT3 | |
| SCHEMBL8713254 | 0.76 | SMN1; SMN2 (0.47) | LDHAALDH1A1LMNAKDM4E | |
| SCHEMBL8713251 | 0.76 | SMN1; SMN2 (0.47) | LDHAALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |