Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278177 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL27905589 | 0.80 | F11 (0.56) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL2423008 | 0.78 | LPL (0.52) | SMN1; SMN2MAPTTP53ALDH1A1KDM4E | |
| SCHEMBL9580386 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL8649755 | 0.76 | RAB9A (0.57) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL10615812 | 0.75 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL8718765 | 0.74 | ALDH1A1 (0.35) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL2560337 | 0.74 | NPC1 (0.53) | RAB9ANPC1ATMMEN1KMT2A | |
| SCHEMBL14668828 | 0.74 | CA2 (0.54) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL30518373 | 0.74 | NPC1 (0.53) | RAB9ANPC1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847149-A | Thiadiazole derivatives, process for their preparation, and their use as precursors for the production of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |