Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718162 | 0.82 | L3MBTL1 (0.38) | SMN1; SMN2KDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL8718165 | 0.78 | LMNA (0.40) | SMN1; SMN2KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL8719002 | 0.77 | L3MBTL1 (0.37) | SMN1; SMN2L3MBTL1KMT2AMEN1SRD5A2 | |
| SCHEMBL3977324 | 0.74 | CRBN (0.42) | SMN1; SMN2KDM4ERAB9AL3MBTL1MAPT | |
| SCHEMBL4070816 | 0.74 | SRD5A2 (0.58) | S1PR5SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1099201 | 0.73 | HTR2C (0.46) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL11366826 | 0.72 | ALDH1A1 (0.45) | S1PR5SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL8715545 | 0.72 | PDE4A (0.39) | SMN1; SMN2L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL6588410 | 0.72 | CYP2D6 (0.46) | SMN1; SMN2KDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL22815698 | 0.70 | ADRA1D (0.40) | L3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |