Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL870704 | 0.84 | HTR3E (0.70) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL29998630 | 0.84 | HTR3E (0.70) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL8984715 | 0.82 | ADRB1 (0.52) | ADRB1AKR1C3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL298843 | 0.82 | MAPT (0.57) | AKR1C3LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3076371 | 0.81 | DRD4 (0.52) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL2383844 | 0.78 | CHKA (0.57) | AKR1C3ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3239961 | 0.77 | HSD11B1 (0.52) | LMNAALDH1A1SMN1; SMN2HTTDRD4 | |
| SCHEMBL5535690 | 0.77 | CA12 (0.55) | AKR1C3SMN1; SMN2DRD4MAPT | |
| SCHEMBL3667964 | 0.77 | L3MBTL1 (0.57) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL4507713 | 0.76 | SIRT6 (0.65) | ADRB1AKR1C3LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | disclosed |