SCHEMBL871964

SCHEMBL871964

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(CNC(N)=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.57
TP53 P04637 1/20 0.57
GLA P06280 1/20 0.57
POLB P06746 2/20 0.53
LMNA P02545 2/20 0.51
GAA P10253 1/20 0.51
CTSD P07339 1/20 0.50
THRB P10828 1/20 0.49
FLT1 P17948 1/20 0.49
FLT4 P35916 1/20 0.49
KDR P35968 1/20 0.49
RXFP1 Q9HBX9 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 2/20 0.46
RORC P51449 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
NOD2 Q9HC29 1/20 0.46
KAT6A Q92794 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15495162 0.82 RXFP1 (0.60) HPGDPOLBGAATHRBFLT1
SCHEMBL18803129 0.82 POLB (0.64) POLBLMNAGAACTSDTHRB
SCHEMBL27490690 0.81 NR1H4 (0.59) LMNAGAAALDH1A1MAPK1
SCHEMBL7797528 0.81 GAA (0.59) POLBLMNAGAACTSDTHRB
SCHEMBL9414560 0.81 POLB (0.68) TP53POLBGAACTSDTHRB
SCHEMBL16244081 0.81 KDM4E (0.62) HPGDTP53GLAPOLBGAA
SCHEMBL11821460 0.81 HPGD (0.71) HPGDTP53GLAPOLBALDH1A1
SCHEMBL5402610 0.80 GAA (0.52) HPGDPOLBGAACTSDTHRB
SCHEMBL19358864 0.79 HPGD (0.64) HPGDTP53GLAPOLBLMNA
SCHEMBL19358848 0.79 HPGD (0.71) HPGDTP53GLAPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1195414-C Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2005-04-06 CN claimed
CN-1326317-A Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2001-12-12 CN claimed
EP-3372081-A2 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS Bayer CropScience Aktiengesellschaft (DE) 2018-09-12 EP disclosed
EP-2958430-B1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES BAYER CROPSCIENCE AG (DE) 2017-12-27 EP disclosed
US-9848602-B2 Use of prothioconazole to induce host defence responses BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-12-26 US disclosed
WO-2017186577-A1 TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME BAYER CROPSCIENCE AKTIENGESSELSCHAFT (DE) 2017-11-02 WO disclosed
EP-3238540-A1 TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME Bayer CropScience Aktiengesellschaft (DE) 2017-11-01 EP disclosed
US-20160270394-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-09-22 US disclosed
US-9414595-B2 Use of anthranilic acid diamide derivatives for pest control in transgenic crops BAYER CROPSCIENCE AG (DE) 2016-08-16 US disclosed
US-20150373975-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-12-31 US disclosed
EP-2958430-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES Bayer CropScience AG (DE) 2015-12-30 EP disclosed
EP-2468097-A1 Use of Isothiazolecarboxamides to create latent host defenses in a plant Bayer CropScience AG (DE) 2012-06-27 EP disclosed
EP-2460406-A1 Use of fluopyram for controlling nematodes in nematode resistant crops Bayer CropScience AG (DE) 2012-06-06 EP disclosed
WO-2012038480-A2 USE OF BIOLOGICAL OR CHEMICAL CONTROL AGENTS FOR CONTROLLING INSECTS AND NEMATODES IN RESISTANT CROPS BAYER CROPSCIENCE AG (DE) 2012-03-29 WO disclosed
WO-2011107443-A1 USE OF PROPINEB FOR PHYSIOLOGICAL CURATIVE TREATMENT UNDER ZINC DEFICIENCY BAYER CROPSCIENCE AG (DE) 2011-09-09 WO disclosed
US-20110218107-A1 Use of Propineb for Physiological Curative Treatment Under Zinc Deficiency BAYER CROPSCIENCE AG (DE) 2011-09-08 US disclosed
US-20100273874-A1 USE OF PROPINEB AS BIRD REPELLENT BAYER CROPSCIENCE AG (DE) 2010-10-28 US disclosed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP disclosed
CN-1195414-C Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2005-04-06 CN disclosed
CN-1326317-A Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2001-12-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218107-A1 Use of Propineb for Physiological Curative Treatment Under Zinc Deficiency PLPBP, ZFR, CTRB1 HPGD 932/4885TP53 3457/4885GLA 1483/4885
US-20160270394-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS PLPBP, PNPO, PNMT HPGD 2413/4885TP53 4798/4885GLA 2517/4885
US-20100273874-A1 USE OF PROPINEB AS BIRD REPELLENT NMBR, EPHB4, EPHB1 HPGD 4310/4885TP53 4544/4885GLA 3721/4885
US-20150373975-A1 USE OF PROTHIOCONAZOLE TO INDUCE HOST DEFENCE RESPONSES SLC11A2, ERG28, CYTH3 HPGD 1040/4885TP53 4758/4885GLA 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.