SCHEMBL873142

SCHEMBL873142

CC(C)C(O)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.61
TAAR1 Q96RJ0 4/20 0.54
SIGMAR1 Q99720 4/20 0.54
SLC6A2 P23975 3/20 0.54
SLC6A4 P31645 2/20 0.54
SLC6A3 Q01959 2/20 0.54
MAOA P21397 1/20 0.54
CYP2A6 P11509 1/20 0.54
ADORA2A P29274 1/20 0.54
ADORA1 P30542 1/20 0.54
SLC18A2 Q05940 1/20 0.50
CYP2D6 P10635 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
CYP1A2 P05177 1/20 0.46
EPHX1 P07099 1/20 0.46
ADRA2B P18089 1/20 0.45
ADRA2C P18825 1/20 0.45
HTR2A P28223 1/20 0.45
ADRA1A P35348 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26085425 1.00 TRPA1 (0.61) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL26085426 1.00 TRPA1 (0.61) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL105769 0.86 TRPA1 (0.57) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL20008956 0.86 TRPA1 (0.57) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL107335 0.86 TRPA1 (0.61) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL108646 0.85 TRPA1 (0.58) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL17429779 0.85 TRPA1 (0.55) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL17429775 0.85 TRPA1 (0.55) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
SCHEMBL15640342 0.83 SLC6A2 (0.57) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL4646601 0.82 TRPA1 (0.57) TRPA1TAAR1SIGMAR1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114574264-B Composite extreme pressure antiwear agent and preparation method and application thereof 中国石油天然气股份有限公司 2023-04-07 CN claimed
CN-114574264-A Composite extreme pressure antiwear agent and preparation method and application thereof 中国石油天然气股份有限公司 2022-06-03 CN claimed
US-20190010293-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
US-20190010427-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-20260069734-A1 FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS ARYLESSENCE INC (US) 2026-03-12 US disclosed
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS PBC (US) 2026-01-29 US disclosed
US-12496370-B2 Freshening compositions comprising controlled release modulators Arylessence, Inc. (US) 2025-12-16 US disclosed
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 US disclosed
US-20250236810-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES OSMO LABS, PBC 2025-07-24 US disclosed
WO-2025049824-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO disclosed
WO-2005048743-A1 FOOD PRODUCTS CONTAINING A FRUIT COMPONENT TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-02 WO disclosed
US-20040007252-A1 Cleaning layer having a 180 degrees peeling adhesion to a silicon wafer of </= 0.20 N/10 mm after receiving an active energy and an adhesive layer NITTO DENKO CORPORATION (JP) 2004-01-15 US disclosed
EP-1377394-A1 LABEL SHEET FOR CLEANING AND CONVEYING MEMBER HAVING CLEANING FUNCTION Nitto Denko Corporation (JP) 2004-01-07 EP disclosed
WO-2002083332-A1 LABEL SHEET FOR CLEANING AND CONVEYING MEMBER HAVING CLEANING FUNCTION NITTO DENKO CORPORATION (JP) 2002-10-24 WO disclosed
EP-0919607-A2 Lubricant for mechanical working of materials and additive for the lubricant Rhenus Lub GmbH & Co. KG (DE) 1999-06-02 EP disclosed
US-5259966-A Low chlorine overbased calcium salts THE LUBRIZOL CORPORATION (US) 1993-11-09 US disclosed
US-4745116-A INHIBITORS OF SERINE PROTEASE SYNTEX (U.S.A.) INC. (US) 1988-05-17 US disclosed
US-4665070-A SERINE PROTEINASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1987-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 TRPA1 33/4885TAAR1 131/4885SIGMAR1 416/4885
US-20250236810-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING BENZENE DERIVATIVES BBOX1, NISCH, TAS2R4 TRPA1 5/4885TAAR1 1631/4885SIGMAR1 3031/4885
US-20260028554-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING AROMATIC DERIVATIVES TAS2R42, TAS2R4, TAS2R41 TRPA1 85/4885TAAR1 485/4885SIGMAR1 526/4885
US-20260069734-A1 FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS FFAR1, FFAR2, FFAR3 TRPA1 5/4885TAAR1 430/4885SIGMAR1 1035/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 TRPA1 208/4885TAAR1 114/4885SIGMAR1 34/4885
US-20250234910-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING THIENYL ALKANOATE DERIVATIVES TAS1R3, TAS2R5, TRPA1 TRPA1 3/4885TAAR1 103/4885SIGMAR1 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.