Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872445 | 0.94 | CES2 (0.35) | DNM1 | |
| SCHEMBL872790 | 0.87 | — | — | |
| SCHEMBL873956 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28432990 | 0.77 | ADRB2 (0.32) | ADRB2ADRB1ADRB3DNM1 | |
| SCHEMBL10016204 | 0.72 | — | — | |
| SCHEMBL1127954 | 0.71 | DNM1 (0.39) | DNM1 | |
| Hydrochloric Acid SCHEMBL28430115 | 0.69 | DNM1 (0.38) | DNM1 | |
| SCHEMBL1118363 | 0.69 | — | — | |
| SCHEMBL26329272 | 0.69 | CES1 (0.36) | ADRB2ADRB1ADRB3 | |
| SCHEMBL872039 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130202530-A1 | NOVEL RADIOTRACER | IMPERIAL COLLEGE (GB) | 2013-08-08 | — | — | US | claimed |
| EP-2619172-A2 | NOVEL RADIOTRACER | GE Healthcare UK Limited (GB) | 2013-07-31 | — | — | EP | claimed |
| WO-2012040138-A2 | NOVEL RADIOTRACER | GE HEALTHCARE LIMITED (GB) | 2012-03-29 | — | — | WO | claimed |
| US-20130202530-A1 | NOVEL RADIOTRACER | IMPERIAL COLLEGE (GB) | 2013-08-08 | — | — | US | disclosed |
| EP-2619172-A2 | NOVEL RADIOTRACER | GE Healthcare UK Limited (GB) | 2013-07-31 | — | — | EP | disclosed |
| EP-2619171-A2 | NOVEL PRECURSOR | GE Healthcare UK Limited (GB) | 2013-07-31 | — | — | EP | disclosed |
| EP-2619170-A2 | ISOTOPIC CARBON CHOLINE ANALOGS | GE Healthcare UK Limited (GB) | 2013-07-31 | — | — | EP | disclosed |
| US-20130183239-A1 | ISOTOPIC CARBON CHOLINE ANALOGS | IMPERIAL COLLEGE (GB) | 2013-07-18 | — | — | US | disclosed |
| US-20130178653-A1 | NOVEL PRECURSOR OF RADIOLABELLED CHOLINE ANALOG COMPOUNDS | IMPERIAL COLLEGE (GB) | 2013-07-11 | — | — | US | disclosed |
| WO-2012040151-A2 | ISOTOPIC CARBON CHOLINE ANALOGS | GE HEALTHCARE LIMITED (GB) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012040138-A2 | NOVEL RADIOTRACER | GE HEALTHCARE LIMITED (GB) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012040133-A2 | NOVEL PRECURSOR | GE HEALTHCARE LIMITED (GB) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178653-A1 | NOVEL PRECURSOR OF RADIOLABELLED CHOLINE ANALOG COMPOUNDS | CHAT, CEPT1, SLC5A7 | ADRB2 190/4885ADRB1 65/4885ADRB3 69/4885 |
| US-20130183239-A1 | ISOTOPIC CARBON CHOLINE ANALOGS | CEPT1, CHAT, CHKB | ADRB2 1039/4885ADRB1 747/4885ADRB3 366/4885 |
| US-20130202530-A1 | NOVEL RADIOTRACER | CEPT1, SGMS1, SGMS2 | ADRB2 919/4885ADRB1 534/4885ADRB3 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.