SCHEMBL8737972

SCHEMBL8737972

O=C(C[S+]1CCCC1)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.49
ALDH1A1 P00352 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 2/20 0.38
EZH2 Q15910 1/20 0.37
CHRNA7 P36544 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MAPK1 P28482 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
CES1 P23141 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4028699 0.83 KMT2A (0.48) HPGDALDH1A1L3MBTL1LMNASMN1; SMN2
Bromide SCHEMBL482705 0.83 KMT2A (0.48) HPGDALDH1A1L3MBTL1LMNASMN1; SMN2
SCHEMBL686332 0.82 SMN1; SMN2 (0.53) HPGDALDH1A1L3MBTL1LMNASMN1; SMN2
SCHEMBL2754885 0.78 RAB9A (0.40) ALDH1A1SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL2754884 0.78 ERCC5 (0.54) HPGDALDH1A1CA1CA2SMN1; SMN2
SCHEMBL106663 0.76 NPC1 (0.48) HPGDALDH1A1L3MBTL1LMNACA1
SCHEMBL10122612 0.75 GSK3B (0.52) ALDH1A1L3MBTL1LMNACA1CA2
SCHEMBL10122613 0.75 GSK3B (0.52) HPGDALDH1A1LMNACA1CA2
SCHEMBL8792913 0.74 HPGD (0.60) HPGDALDH1A1L3MBTL1LMNACHRNA7
SCHEMBL686213 0.73 PTPN1 (0.56) HPGDALDH1A1SMN1; SMN2MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200192220-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2020-06-18 US disclosed
US-20120129100-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20110269072-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE SAME FUJIFILM CORPORATION (JP) 2011-11-03 US disclosed
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120129100-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE SAME ACTR8, RAD51, ACTR2 HPGD 1593/4885ALDH1A1 2640/4885L3MBTL1 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.